The LASER trial is a randomised, placebo-controlled trial. This means that we will be comparing the effect of 12 months of treatment with an active treatment device with 12 months of treatment with a placebo device. We will recruit 222 patients to the trial. Half (111) will receive an active treatment device and half (111) will receive a placebo device. During the course of the trial neither you nor the trial team will be aware of which treatment you are receiving.

At the completion of the trial, you will be offered the opportunity to continue using an active Airsonett® treatment device for a further 4 years, free of charge, including filter changes and engineering support, regardless of whether you had an active or placebo device during the trial period.