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A new treatment for patients with allergic asthma.

L.A.S.E.R. stands for ‘Laminar Airflow in Severe asthma for Exacerbation Reduction.’

The LASER Trial is a clinical trial for patients with allergic asthma. The trial has been designed to determine whether TLA treatment is effective in reducing the number of asthma attacks suffered by patients and to see if the treatment can improve patient’s asthma control and quality of life. The Trial will include 222 adults, half of whom will be given a TLA device that is working, and the other half will be given a device which has been inactivated (the filtering process will be switched off, although the participants will not be able to tell that this has occurred). Which participant receives the working or deactivated device will be decided by a random process and will be unknown to the researcher and the participant.

To request additional information about the LASER trial or TLA please contact us.

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What is Temperature Controlled Laminar Airflow (TLA?)

TLA is a treatment for patients with allergic asthma who despite taking their asthma medications continue to experience symptoms.

The TLA treatment is delivered by a device called an Airsonett® device.

TLA treatment is designed to significantly reduce the number of allergy particles that are inhaled overnight to allow the lungs time to rest and recover. In patients with allergic asthma these particles are known to cause asthma symptoms and asthma attacks (exacerbations.)


What is The LASER Trial?

The LASER Trial is a clinical trial that has been designed to determine whether TLA treatment is effective in reducing the number of asthma attacks suffered by patients and to see if the treatment can improve patient’s asthma control and quality of life.

The Laser trial has been developed by asthma specialists across the UK.

The trial is a multi-centre, randomised, placebo-controlled trial. 222 patients with allergic asthma will be randomly allocated to receive either an active treatment device or a placebo (inactivated) device for 12 months.

Patients will be reviewed during the 12 month period to see if their asthma symptoms improve and to see if they have required treatment for any asthma attacks.

Results of the trial will help to determine whether this is a treatment that should be offered to all patients with poorly controlled allergic asthma.

The LASER Trial - A breath of fresh air in Asthma!

The LASER Trial is funded by the National Institute for Health Research Health Technology Assessment Programme
(Project number 12/33/28)

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Asthma Patients March 15, 2015